| Dirk Elmendorf | CEO & President | |
| Marise McDermott | President Emeritus | 210.357.1924 |
| Michelle Everidge, Ph.D. | Deputy Director & Chief Operating Officer | 210.357.1888 |
| Bea Abercrombie | Chief Administrative Officer | 210.357.1871 |
| Mendi Etheredge | Chief of Advancement | 210.357.1851 |
| Beth Stricker | Chief Creative Officer | 210.357.1870 |
| Thomas Adams, Ph.D. | Chief Curator & Vice President of Research | 210.357.1852 |
| Helen Holdsworth | Chief of Engagement | 210.357.1890 |
| Vicky Bates | Chief Financial Officer | 210.357.1874 |
| Leslie Ochoa | Vice President of Collections | 210.357.1877 |
| Ann-Marie Camosy Murray | Vice President of Development | 210.357.1894 |
| Michelle Small | Vice President of Human Resources | 210.357.1854 |
| Roger Garcia | Vice President of Sales & Events | 210.357.1866 |
| Ron Davis | Curator of American History | 210.357.1857 |
| Harry Shafer, Ph.D. | Curator of Archeology | 210.863.0141 |
| Bruce Shackelford | Texas History Curator | 210.357.1862 |
| Katherine Nelson Hall | Texas Heritage Curator | 210.357.1861 |
| Rachel Catalano | Art Director | 210.357.1867 |
| Clara Guerrero | Director of Communications | 210.357.1896 |
| Cherub Spivey | Director of Group Experience & Visitor Analytics | 210.357.1913 |
| Mary Margaret McAllen | Director of Humanities | 210.357.1856 |
| Lessli Ruiz | Director of Public Programs | 210.357.1933 |
| Ryan Blum | Director of Sales & Events | 210.357.1925 |
| Pamela Riles | Director of Volunteerism & Community Engagement | 210.357.1891 |
| Matilda Gonzalez | Director of Visitor Experience | 210.357.1923 |
| Aimee Spana | Director of the White Shaman Preserve | 210.357.1918 |
